An inspirational change of personnel at half-time by manager Peter Morris heralded a Lynn victory at The Walks.
The Linnets had been out-fought and out-thought in the first half by a lively Cambridge side who could have easily had the game sewn up by the interval.
But Morris threw on Steve Williams and Simon Mead to replace the ineffective Craig Hopkins and Russell Stock and it brought immediate reward.
Lynn looked a livelier side after the re-start and made their intentions known when Matthew Wright saw a 20-yard free kick beat the wall and fly just the wrong side of the post.
The 139-minute goal famine was ended seven minutes into the second half when Colin Hoyle sent a high ball across the field.
It looked a lost cause but Brett McNamara scampered after it and delivered a
viscous cross for Williams to crash powerfully past Dan Kelly.
Three minutes later the score was doubled as Richard Skelly picked up a free kick midway inside the visitors half and unleashed a ferocious ground hugging shot from 25 yards that flew in off the post.
Cambridge's fluent first half display deserved reward and it came in the final minute when Andy Taylor sent a looping header past James Hollman from Nicky Smith's corner - one of 20 earned by the visitors compared to Lynn's one.
The hosts were overpowered in the first half and were forced to defend in depth with McNamara and Lee Hudson frequently helping out the Lynn defence.
Neil Harris and Simon Ullathorne both failed to test Hollman when well placed and Andy Picher headed over when Hollman flapped at a Smith corner.
Lynn were lucky to escape unpunished when Tony Spearing felled Michael Cheetham after a mix-up between himself and the keeper.
Glyn Roberts had a rare chance for Lynn but his full-blooded ten-yard effort crashed into the midrift of Kelly.
The tight interpassing game of the visitors, interspersed with flowing crossfield moves kept Lynn at full stretch and Pincher should have done better when he allowed Hollman to save after an eight man move.
Lynn showed their first changes of the season to their starting line-up following injury to Martin Matthews in the game against Atherstone.
Wright was switched to wing-back with Pascoe in the centre and Roberts in midfield. Up front there was also a starting place for Hopkins at the expense of Williams.
The big forward was obviously stung into action by his substitute's berth and replied in the best possible fashion.
Lynn: Hollman, Roberts, Skelly, Wright, Hoyle, Spearing, Pascoe, Stock (Mead 45)
Hopkins (Williams 45), McNamara, Hudson. Sub not used - Read
Cambridge: Kelly, Jeffrey, Lockhart, Taylor, Gawthrop (Leete 78), Pincher, Cheetham (Rutter 67), Ullathorne (Cogger 83), Harris, Smith, Chattoe.